H1 Antihistamines, H2 Antagonists, and Proton Pump Inhibitors

This lectures for these objectives occurred on 8/27, 8/30, 8/31, and 9/1.

Link to Handouts

 * Antihistamines

Link to Panopto

 * 8/27 - Antihistamines
 * 8/30 - Antihistamines
 * 8/31 - 2nd Gen Antihistamines & H2 Blockers
 * 9/1 - H2 blockers

Objectives
Edited by Coastermonger 20:24, September 23, 2010 (UTC)

Describe how histamine is synthesized in vivo.
Histamine is synthesized from Histidine via the enzyme Histidine Decarboxylase (HDC). The molecule is subsequently stored primarily in mast cells.



Describe the different types of histamine receptors.
There are 4 types of histamine receptors. All of them are G protein coupled, they differ in their secondary messengers and tissue distribution.